Piperine, an alkaloid found in the spikes and oleoresin of the peppercorn plant, is also present in high concentration in the skin of the pepper berries.

Piperine is also found in black pepper and similar plants, and, even though piperine obtained from natural sources is about 98% pure, it is, for chemical and medical purposes, laboratory-produced.

Black pepper (Piper nigrum) is a flowering vine in the family Piperaceae, cultivated for its fruit, which is usually dried and used as a spice and seasoning. The fruit, known as a peppercorn when dried, is approximately 5 millimetres (0.20 in) in diameter, dark red when fully mature, and, like all drupes, contains a single seed. Peppercorns, and the ground pepper derived from them, may be described simply as pepper, or more precisely as black pepper (cooked and dried unripe fruit), green pepper (dried unripe fruit) and white pepper.

The primary value of piperine in health supplements is its ability to enhance the bioavailability of some other vitamins and minerals. This mechanism is still being studied, but piperine is known to inhibit the enzymes P-glycoprotein and CYP3A4 in humans. These enzymes are involved in the metabolism and transport of various metabolites. Animal studies also show that piperine inhibits CYP 450 enzymes that metabolize many drugs. In particular, piperine may increase the bioavailability of curcumin by a factor of 20.

1. Treatment for arthritis, rheumatism and skin disease or wound healing;

2. Losing weight, its ability to increase in the metabolic rate of the body;

3. Clearing heat and diuretic, expectorant, sedative and analgesic;

4. Treating acute conjunctivitis, bronchitis, gastritis, enteritis and urinary stones;

5. Enhancing immunity and supporting the intestinal absorption of nutrients.

There are several Similar Products available. Here are a few of the most common types:

Celery Seed Extract :This product treats arthris,rheumatism and gout,lower blood pressure and blood fat,good for loss weight,reduce inflammation,lower anxiety and calm the nerves,etc .

Curcumin :This product anti-virus,anti-bacteria,anti-therosclerotic,anti-inflammation,anti-cancer,etc.

Gotu Kola Extract: This product is antibacterial and anti-inflammatory,clear heat and remove dampness,diuretic to reduce swelling,promote the repair of skin damage,ect .

Elderberry Extract: This product prevent the cardiovascular diseases,quench free radical,antioxidant,and anti-aging,treatment for mild inflammation of the mucous membranes of mouth and throat,etc.

Horsetail Extract: This product is good action on diuretic and detoxification, anti-virus and inflammation,arrest cough,stop bleeding and promote wound healing,etc .

White Willow Bark Extract: This product has the same effect on the body as aspirin without any of the side effects,anti-inflammation,fever relief ,antirheumatism,control arthritis discomforts,etc.