N-Acetyl-L-Cysteine

  • Name: N-Acetyl-L-Cysteine
  • CAS: 616-91-1
  • Molecular Formula: C5H9NO3S
  • Molecular Weight: 163.2
  • Description

    White crystals or crystalline powder; strongly acid taste. Freely soluble in water.
    Soluble in ethanol, practically insoluble in ether.
    Solubility(H2O, g/100g):17(20°),80(40°),260(60°)

  • Function

    Biological reagents, bulk drugs, the sulfhydryl group (-SH) contained in the molecule can break the disulfide chain (-S-S) that connects the mucin peptide chain in mucus sputum. Mucin becomes a peptide chain of small molecules, which reduces the viscosity of sputum; it can also break DNA fibers in purulent sputum, so it can not only dissolve white viscous sputum but also purulent sputum. It is used in biochemical research, as a phlegm solubilizer and an antidote for acetaminophen poisoning in medicine. The mechanism of action is that the sulfhydryl group contained in the product’s molecular structure can break the disulfide bond in the mucin polypeptide chain in mucinous sputum, decompose the mucin, reduce the viscosity of the sputum, and make it liquefied and easy to cough up. It is suitable for patients with acute and chronic respiratory diseases whose sputum is thick and difficult to cough up, as well as a large number of sticky sputum blockages that cause severe symptoms due to difficulty in sucking

    Antioxidants,antidote and mucus decomposing agents inhibit HIV replication; serve as substrates for microsomal glutathione transferases,treat chronic broncitis and dissolve white viscous sputum,etc .

    Item

    Specification

    Test result

    Appearance

    White, crystalline powder, having a slight acetic odor

    Conforms

    Specific Rotation〔α〕D20

    +21.3° to +27.0°

    +23.6°

    Chloride (Cl)

    Not more than 0.04%

    < 0.04%

    Ammonium (NH4)

    Not more than 0.02%

    < 0.02%

    Sulfate (SO4)

    Not more than 0.030%

    < 0.020%

    Iron (Fe)

    Not more than 20ppm

    < 10ppm

    Heavy metals ( Pb),

    Not more than 10ppm

    < 10ppm

    Arsenic (As2O3)

    Not more than 1ppm

    < 1ppm

    Other amino acid


    Chromatographically 
    Not detectable


    Conforms

    Loss on Drying

    Not more than 0.50%

    0.13%

    Residue on ignition(sulfated)

    Not more than 0.20%

    0.05%

    Assay

    98.5 to 101.0%

    99.66%

    pH

    2.0 to 2.8

    2.2

    Melting point

    106 to 110ºC

    108 to 109ºC

    Conclusion: The product conforms to the specification of  AJI92 standards.

  • Related Products

    There are several Related Products available. Here are a few of the most common types:

    Carbocisteine : This product resist acne,cure of chronic tracheitis,emphysema and pulmonary,hair finishing agent and adjusting agent,anti inflammation,etc

    L-Cysteine HCL Monohydrate : This product is antioxidant,,anti inflammation,and radiopharmaceuticals,treat toxic hepatitis,thrombocytopenia and skin ulcer,prevent hepatic necrosis,also treat tracheitis and reduce phlegm,etc.

    L-Cystine : This product promote the oxidation and the proliferation of white blood cells,make the liver function vigorous,treat dysentery,typhoid fever,influenza,asthma neuralgia and various toxic diseases,etc

    Taurine : This product is anti inflammation and antioxidant,enhance immunization function,treatment of rheumatoid arthritis,bronchitis,protect liver,relief heat from the body,etc.

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